izvinite što ću vam na engleskom deo iz reference: Report ff the Scientific Commitee for food EU Commission , Directorate – General Industry 1993…The potential carcinogenicity of aflatoxins has been examined in a large number of population studies,
both cohort and correlation studies. Most of them were carried out in Africa and Asia, where
substantial quantities of aflatoxins occur in basic foodstuffs. It can be concluded that there is good
accordance between the results of practically all the existing population studies, even though these
have been carried out in population groups where other known risk factors for liver cancer such as
hepatitis B-virus and alcohol, vary considerably. IARC concluded in 1993 that there is sufficient
evidence in humans for the carcinogenicity of naturally occurring mixtures of aflatoxins, and for the
carcinogenicity of aflatoxin B1. The overall evaluation of IARC was: “Naturally occurring aflatoxins
are carcinogenic to humans (Group 1)“. Aflatoxins, especially B1, have been tested extensiveley for genotoxicity. Aflatoxin B1 is consistently . Aflatoxins, especially B1, have been tested extensiveley for genotoxicity. Aflatoxin B1 is consistently found to be genotoxic, producing adducts in humans and animals in viva and chromosomal anomalies infound to be genotoxic, producing adducts in humans and animals in viva and chromosomal anomalies in rodents and, in a single study, in rhesus monkeys in vim. It induces DNA damage, gene mutation,chromosomal anomalies and cell transformation in mammalian cells in vitro, in insects, lower eukaryotes and bacteria. Fewer studies have been performed, in descending order, with aflatoxins B2, G1 and G2 but these showed a comparable genotoxic profile.

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